Study finds breast cancer driver, HER2, in 3 percent of lung cancers
The Lung Cancer Mutation Consortium at the University of Colorado Cancer Center reports this week in the journal Cancer that 24 of 920 patients (3 percent) with advanced-stage lung cancer had mutations...
View ArticleMaryland scientists research gene linked to depression
Although there are medications to treat depression, many scientists aren't sure why they're effective and why they don't work for everyone.
View ArticleGene therapy via skin could treat many diseases, even obesity
A research team based at the University of Chicago has overcome challenges that have limited gene therapy and demonstrated how their novel approach with skin transplantation could enable a wide range...
View ArticleNew 3D-drug screening aims to ease economic burden of rare muscle diseases
Rare muscle diseases have a devastating impact on the affected individual and their families, but 3-D-drug screening could lead to better medicines being developed which would also relieve the huge...
View ArticleGene therapy with BMP4 protects against weight gain and insulin resistance in...
There was no weight gain, despite a higher energy intake, and insulin sensitivity was increased. These are the results from experiments on mice that had elevated levels of the protein BMP4 following...
View ArticleFDA approves personalized cellular therapy for advanced leukemia
In a landmark decision for the field of cancer immunotherapy, the U.S. Food and Drug Administration (FDA) today approved a personalized cellular therapy developed by the University of Pennsylvania and...
View ArticleUS clears breakthrough gene therapy for childhood leukemia
Opening a new era in cancer care, U.S. health officials have approved a breakthrough treatment that genetically engineers patients' own blood cells into an army of assassins to seek and destroy...
View ArticleElectric genes hope to fix a broken heart
Broken hearts have long influenced songsters and poets, but scientists have also been occupied by its literal meaning and are now hoping to use electric gene therapy as a revolutionary new treatment...
View ArticleRare genetic cause of peritoneal mesothelioma points to targeted therapy
Mesothelioma is a rare and aggressive tumor that, in many cases, results from exposure to asbestos. But over the last several decades, other causes of the disease have emerged, including treatment with...
View ArticleMesenchymal stem cells offer novel treatment approach for Crohn's disease...
A growing body of clinical evidence shows that transplantation of a patient's own mesenchymal stem cells (MSCs) to achieve a cure and prevent recurrent of Crohn's disease-related fistula can be a safe...
View ArticleNew assay leads to step toward gene therapy for deaf patients
Scientists at Oregon State University have taken an important step toward gene therapy for deaf patients by developing a way to better study a large protein essential for hearing and finding a...
View ArticleNew study shows promise of gene therapy to treat alcoholism
Researchers used gene transfer to block the expression of one of the two main enzymes that break down alcohol in the liver, leading to the accumulation in liver cells of acetaldehyde, a metabolic...
View ArticleResearch predicts how patients are likely to respond to DNA drugs
Research carried out by academics at Northumbria University, Newcastle could lead to improvements in treating patients with diseases caused by mutations in genes, such as cancer, cystic fibrosis and...
View ArticleNew gene delivery approach could allow long-term persistence in proliferating...
Researchers added a scaffold/matrix attachment region (S/MAR) to a conventional adeno-associated virus (AAV) vector used for gene transfer, and the modified vectors were able to establish colonies and...
View ArticleGene therapy restores hearing and balance in Usher syndrome
Scientists from the Institut Pasteur, Inserm, the CNRS, Collège de France, University Pierre et Marie Curie, and University Clermont Auvergne, have recently restored hearing and balance in a mouse...
View ArticleGene therapy improved left ventricular and atrial function in heart failure...
Heart function improved by up to 25 percent in a trial using gene therapy to reverse cardiac damage from congestive heart failure in a large animal model, Mount Sinai researchers report. This is the...
View ArticleGene therapy helps boys with 'Lorenzo's Oil' disease
The fledgling field of gene therapy has scored another win: An experimental treatment seemed to help boys with the inherited nerve disease featured in the movie "Lorenzo's Oil."
View ArticleLancet Commission advises reforming experimental therapies
A Lancet commission of senior scientists has demanded root and branch reform of the way experimental therapies associated with Regenerative Medicine are carried out.
View ArticleMini form of replacement gene can delay degeneration in leber congenital...
A new study demonstrates success in using a shortened form of the CEP290 gene for gene therapy in a mouse model of Leber congenital amaurosis type 10 (LCA10), a retinal degenerative disorder that...
View ArticleResearchers identify genetic drivers of most common form of lymphoma
Lymphoma is the most common blood cancer, but the diagnosis belies a wildly diverse and little understood genetic foundation for the disease that hampers successful treatment.
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