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Conquering the lysosomal storage disorders with genetic engineering

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(Medical Xpress)—The motivation by fear, anger, and love to preserve self, kin, and others perches near the pinnacle of our existence. Triumph in the face of a seemingly insurmountable medical adversity by the creation of some tangibly successful treatment, virtually out of thin air, invariably strings together countless moments of courage and heroism to cut a continuous path of sheer human elegance through time that is a privilege to behold. The movie 'Lorenzo's Oil', and the book 'My Brother's Keeper', are two such popular accounts of families who brought the fight and won the fight against rare neurodegenerative disorders; a third is the now unfolding story of a family fighting against a debilitating lysosomal storage diseases known as Sanfilippo Syndrome, or MPSIIIa (mucopolysaccharidosis IIIa).

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