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Gene-modified, virus-specific T cell therapy shows promise in treating lymphoma, with little toxicity

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In a first-of-its-kind clinical study, Baylor College of Medicine evaluated the safety, survival and anti-tumor activity of tumor-specific T cells rendered resistant to transforming growth factor β (TGFβ), in patients with Epstein Barr Virus (EBV) positive lymphoma. The results appear in the Journal of Clinical Oncology.

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